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产品名称:
Lens Culinaris Agglutinin (LCA), Unconjugated, 10 mg/扁豆凝集素
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别名:
扁豆凝集素
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产品描述:
Lens culinaris agglutinin LCA LcH is composed of four subunits - two of about 17 kDa and two of 8 kDa. LCA recognizes sequences containing α-linked mannose residues but recognizes additional sugars as part of the receptor structure, giving it a narrower specificity than Con A. An α-linked fucose residue attached to the N-acetylchitobiose portion of the core oligosaccharide significantly enhances affinity. By exploiting this narrower specificity, glycoproteins and glycopeptides can be subfractionated with LCA after initial isolation with Con A.LCA has been found to be one of the most effective agents in preventing skin allograft rejection in model systems. LCA has been used to purify numerous glycoproteins, including immunoglobulins, histocompatibility antigens, and α2-macroglobulin.Inhibiting/Eluting Sugar: mixture of 200 mM α-methylmannoside/200 mM α-methylglucoside
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实验应用:
Immunohistochemistry / Immunocytochemistry,Immunofluorescence,Blotting Applications,Glycobiology,Mitogenic Stimulation
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推荐稀释度:
Although many buffers can be employed for reconstituting and diluting this lectin, 10 mM HEPES buffered saline, pH 8.5, 0.1 mM CaCl2 is recommended. For preserving solutions stored at 4°C, 0.08% sodium azide can be used.
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偶联:
Unconjugated
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产地:
美国
服务热线
15195831611
