产品描述
EiDD1931 is a ribonucleoside analog with antiviral activity.It inhibits replication of severe acute respiratory syndrome coronavirus (SARS-CoV) in Vero 76 cells, Middle East respiratory syndrome coronavirus (MERS-CoV) in Calu-3 2B4 cells, and SARS-CoV-2 in Vero cells (IC50s =0.1, 0.15 and 0.3 μM, respectively)
别名
Beta-d-N4-hydroxycytidine;EIDD-1931
参考文献
[1]Urakova N, et al. β-d-N4-Hydroxycytidine Is a Potent Anti-alphavirus Compound That Induces a High Level of Mutations in the Viral Genome. J Virol. 2018 Jan 17;92(3). pii: e01965-17.
引用文献
[1]Li Y, Liu M, Yan Y, et al. Molnupiravir and Its Active Form, EIDD-1931, Show Potent Antiviral Activity against Enterovirus Infections In Vitro and In Vivo. Viruses. 2022, 14(6): 1142
储存和溶解度
DMSO:230 mg/mL (887 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years