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IBL #27412 Human Total Angiotensinogen Assay Kit
  • 品牌:IBL
  • 型号:96 Well
  • 货号:27412
  • 价格: ¥9760/盒
  • 发布日期: 2023-09-25
  • 更新日期: 2024-08-30
产品详请
产地
品牌 IBL
货号 27412
用途
英文名称
包装规格 96 Well
纯度 %
CAS编号
别名
分子式
是否进口
Product Code 27412
Product Name Human Total Angiotensinogen Assay Kit - IBL
Intended Use Research reagents
Measuring Method ELISA
Conjugate HRP
Species Human
Measuring Samples Serum, EDTA-plasma, Urine, Cell culture supernatant ( ※ Additional EIA buffer may be required depending on your samples. The EIA buffer is available with charge. Please refer to the datasheet for the details.)
Measurement Range 0.31 ~ 20 ng/mL
Primary Reaction 60 minutes at 37 ℃
Secondary Reaction 30 minutes at 37 ℃
Sensitivity 0.03 ng/mL
Specificity Substance Cross-reactivity
Human Angiotensinogen 100.0%
Angiotensin I < 0.1 %
Angiotensin II < 0.1 %
Angiotensin III < 0.1 %
Angiotensin IV < 0.1 %
Angiotensin (1-7) < 0.1 %
Angiotensin (1-9) < 0.1 %
Human albumin < 0.1 %
Human IgG < 0.1 %
Human Angiopoietin-like 3 < 0.1 %
Storage Condition 2 - 8 ℃
Poisonous and Deleterious Substances Not Applicable
Cartagena Not Applicable
Measuring Service Not Available
Package Size 1 96 Well
Remarks1 An additional EIA buffer may be required depending on your samples.
The EIA buffer is available with charge. Please refer to the details on the datasheet.
As the composition of EIA buffer may be different on each product, please use the following product specific EIA buffer for additional use.

Product Code: 27412D100
Product Name: Human Angiotensinogen EIA buffer 100
Size: 100 mL

Product Description

        Angiotensinogen is the precursor of angiotensin and is cleaved into angiotensin I and II in the renin-angiotensin system, and it has long been reported to play an important role in controlling blood pressure. In recent years interest related to the role of the renin-angiotensin system in arterial pressure control and the pathophysiology of hypertension has been shifting to its local role in various tissues. Among the studies urinary excretion of angiotensinogen in a rat model of angiotensin II (AII)-dependent hypertension has been reported to be a marker of the activity of the local intrarenal renin-angiotensin system. Intrarenal AII increases to an extent in AII-dependent hypertension that cannot be explained by the plasma AII equilibration alone, and two mechanisms, an increase in intracellular uptake of AII and an increase in intrarenal expression of angiotensinogen, have been proposed to explain it.

The kit can quantitatively measure Human Total Angiotensinogen.